5AM Venture Management, LLC

Q3 2025 13F Holdings

  • Location
    san francisco, CA
  • Num holdings

    25

  • Value ($000)

    $273,045

  • Date Filed
    11/14/2025
  • Form type
    13F-HR
  • CIK
    0001799883
  • All SEC filings
  • Note
    Holdings aggregated across “other managers” listed in original SEC filing, see here for detailed holdings broken out by other managers
Compare Q3 2025 to
Select Quarter
Issuer Name
Class
CUSIP
VALUE
%
Shares
Principal
Option Type
SKYE
SKYE

SKYE BIOSCIENCE INC

COM NEW
83086J200
$38.05 M
14 %

9,681,763

TRDA
TRDA

ENTRADA THERAPEUTICS INC

COM
29384C108
$24.69 M
9 %

4,256,379

---

PHARVARIS N V

COM
N69605108
$19.90 M
7 %

797,600

---

CAMP4 THERAPEUTICS CORP

COM
13463J101
$17.61 M
6 %

5,869,091

CNTA
CNTA

CENTESSA PHARMACEUTICALS PLC

SPONSORED ADS
152309100
$16.51 M
6 %

680,945

VRDN
VRDN

VIRIDIAN THERAPEUTICS INC

COM
92790C104
$15.90 M
6 %

736,595

ELVN
ELVN

ENLIVEN THERAPEUTICS INC

COM
29337E102
$15.81 M
6 %

772,477

EYPT
EYPT

EYEPOINT PHARMACEUTICALS INC

COM NEW
30233G209
$14.95 M
6 %

1,050,000

DNTH
DNTH

DIANTHUS THERAPEUTICS INC

COM
252828108
$14.36 M
5 %

365,053

---

TYRA BIOSCIENCES INC

COM
90240B106
$13.14 M
5 %

939,298

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